Endocrine Abstracts

Background: The diagnosis of PHPT and chronic HypoPT is still challenging, mainly due to the wide spectrum of clinical and biochemical presentation and the lack of validated diagnostic index in literature. The serum Ca/P ratio has been proposed as an accurate tool to diagnose PHPT in a small sample of patients, while no data is available about its possible application for HypoPT.Aim: To validate the serum Ca/P ratio as a diagnostic index for PHPT and to ...

Background: Patients affected by gastroenteropancreatic-neuroendocrine tumors (GEP-NETs) present an increased risk of bone fragility due to several factors, such as bone metastases, vitamin D deficiency, hormonal secretion, medical and surgical treatments. Although patients with well-differentiated GEP-NETs generally present a long life-expectancy, occurrence of fragility fractures could significantly impair quality of life.Objectives: The study aims to ...

Background: Primary hyperparathyroidism (PHPT) is the third most common endocrine disease and the most frequent cause of hypercalcemia in outpatients with an estimated incidence of 20/100 000/year and prevalence in the general population of 0.1%–0.4%. Parathyroidectomy (PTX) is the only treatment that can achieve PHPT cure but a few medications can be used to control calcium levels, bone and kidney impairment.Aims: 1) To assess costs associated with...